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Brain-Computer Interfaces (BCIs)

Reviewed by the HeyPsych Medical Review Board

Board-certified psychiatrists and mental health professionals

Indications

Primary Indications

Severe motor impairmentALS communicationLocked-in syndromeStroke motor rehabilitationAssistive device control

Mechanism

BCIs work by recording brain activity (via EEG, ECoG, or implanted electrodes), decoding neural signals, and translating them into commands for external devices or feedback systems. Closed-loop BCIs can deliver stimulation back to the brain, potentially modulating circuits relevant to mood, movement, or cognition.

Protocol

Preparation

Screening for medical eligibility, training in BCI use, surgical preparation if invasive.

Procedure

  1. Recording of brain signals via electrodes or sensors
  2. Signal processing and decoding
  3. User training with device control or neurofeedback
  4. Ongoing adjustments for performance optimization

Frequency: Varies by application: daily training in rehabilitation, continuous for communication implants

Duration: 30–180 minutes per session (non-invasive); ongoing for implantable BCIs

Total Treatment Time: Weeks to months of training and adaptation

Equipment

  • EEG or ECoG recording systems
  • Implantable electrode arrays (for invasive systems)
  • Signal decoding software
  • Assistive devices (computer cursor, robotic arm, text-to-speech system)

Session Structure

pre session: Calibration and baseline signal acquisition

training phase: User engages in BCI tasks (cursor control, spelling, robotic movement)

post session: Performance review, retraining, and adjustments

home practice: Daily training for adaptation where applicable

Expected Outcomes

Immediate

  • Basic control of cursor or device
  • Initial communication output

Short Term

  • Improved accuracy with practice
  • Enhanced user-device adaptation

Long Term

  • Restoration of meaningful communication
  • Improved independence
  • Potential cognitive/emotional modulation

Side Effects

common

  • Fatigue
  • Frustration from training
  • Skin irritation from electrodes

uncommon

  • Seizures during invasive recording
  • Headaches

rare

  • Infection or hemorrhage (invasive implants)
  • Device malfunction

Contraindications

absolute

  • Active infection (for invasive implants)
  • Unfit for neurosurgery

relative

  • Severe cognitive impairment limiting training ability
  • Uncontrolled seizure disorder

special considerations

  • Long-term device safety still under investigation
  • User motivation and support crucial for success

Patient Selection

ideal candidates

  • ALS patients with preserved cognition
  • Locked-in patients seeking communication channels
  • Stroke survivors with rehabilitation potential

screening required

  • Neurological exam
  • Neuroimaging (for implant planning)
  • Cognitive and motivation assessment

Training Requirements

practitioner

  • Neurosurgeons (for implants)
  • Neuroengineers and technicians
  • Rehabilitation therapists

facility

  • Clinical neurotechnology lab
  • Rehabilitation clinic
  • Hospital surgical suite (for invasive BCI)

Research Evidence

studies

  • Hochberg et al. (2012): Pioneering work with implanted BCI enabling paralyzed patients to control robotic arms.
  • Recent Synchron (Stentrode) trials show safe minimally invasive vascular-implanted BCI for communication.
  • Non-invasive BCIs widely studied in stroke motor rehabilitation.

limitations: Small samples, high technical complexity, lack of long-term safety and efficacy data.

Cost Considerations

typical session cost: Experimental only; currently research funded

total treatment cost: Projected high costs for invasive devices

insurance coverage: Not covered

cost effectiveness: Unknown; investigational only

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Integration Support

concurrent therapies

  • Speech and language therapy
  • Occupational therapy
  • Neurorehabilitation programs

lifestyle recommendations

  • Consistent training
  • Caregiver and social support
  • Engagement in rehabilitation routines

Special Populations

👶Pregnancy

Not studied

Clinical Notes

  • Invasive BCIs require ongoing neurosurgical monitoring.
  • User training and motivation are critical for success.
  • Regulatory frameworks evolving rapidly; some devices have Breakthrough Device designation.
  • May overlap with neurostimulation devices in psychiatric research.

References

Hochberg et al. (2012), NatureSynchron BCI Clinical TrialReview on BCIs in rehabilitation

This treatment information is for educational purposes only. Treatment decisions should be made in consultation with qualified healthcare professionals based on individual circumstances, symptoms, and medical history. Do not attempt treatment without professional guidance.

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