Indications
Primary Indications
Treatment and prevention of vitamin B6 deficiencyPyridoxine-responsive sideroblastic anemiaPrevention of isoniazid-induced neuropathyAdjunct in pregnancy-related nausea and vomiting
Vitamin B6, also known as pyridoxine, is a water-soluble vitamin essential for amino acid metabolism, neurotransmitter synthesis, hemoglobin production, and regulation of homocysteine levels.
Reviewed by the HeyPsych Medical Review Board · Reviewed November 24, 2025
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Used for
Also prescribed for (off-label)
Common use
Vitamin B6 is used for Treatment and prevention of vitamin B6 deficiency. The full guide below has the details.
How many people in 100 notice each one in clinical studies. Many early side effects fade within a few weeks.
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Safe at recommended dietary intakes; used therapeutically for morning sickness
General information, not advice for your case. Talk it through with your prescriber or pharmacist.
Sensory neuropathy (at doses >500 mg/day for prolonged periods)
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Everything we know about Vitamin B6 (Pyridoxine), section by section.
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With: Isoniazid
Risk: Can cause B6 deficiency and neuropathy
Action: Supplement with pyridoxine
With: Levodopa
Risk: High-dose pyridoxine can reduce levodopa efficacy unless given with carbidopa
Action: Avoid high-dose supplementation without medical supervision
This treatment information is for educational purposes only. Treatment decisions should be made in consultation with qualified healthcare professionals based on individual circumstances, symptoms, and medical history. Do not attempt treatment without professional guidance.
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