A non-invasive neuromodulation technique using focused or low-intensity ultrasound waves to modulate brain activity, currently under investigation for psychiatric and neurological disorders.
Reviewed by the HeyPsych Medical Review Board · Reviewed November 24, 2025
Choose a condition to see how it's used for it.
Used for
Also prescribed for (off-label)
Common use
Transcranial Ultrasound is used for Investigational for depression. The full guide below has the details.
How many people in 100 notice each one in clinical studies. Many early side effects fade within a few weeks.
Choose what applies to you.
Avoid until safety data are available
General information, not advice for your case. Talk it through with your prescriber or pharmacist.
Unknown long-term effects (under investigation)
Thoughts of suicide? Call or text 988, any time.
Everything we know about Transcranial Ultrasound (TUS), section by section.
12 chapters · about 12 min to read it all. Open any one.
Frequency: Not standardized; varies in research protocols.
Duration: Typically 10–40 minutes per session.
typical session cost: Not established (research use only)
total treatment cost: Not established
insurance coverage: Not covered; experimental
cost effectiveness: Unknown until clinical efficacy is proven
Efficacy and safety not yet established in large randomized clinical trials.
This treatment information is for educational purposes only. Treatment decisions should be made in consultation with qualified healthcare professionals based on individual circumstances, symptoms, and medical history. Do not attempt treatment without professional guidance.
Thinking about Transcranial Ultrasound (TUS)? A prescriber can tell you if it fits.
Find a psychiatrist