HeyPsych
Find SupportPractice ArchitectBrowseSearch

If you're in crisis, help is available 24/7

Call or text 988|More resources
HeyPsych

Better mental health starts with better decisions.

Learn about our clinical review process

Explore

  • Conditions
  • Treatments
  • Tools
  • Find Care

Resources

  • Learn
  • Assessments
  • Support & Crisis
  • For Clinicians

Company

  • About
  • Privacy
  • Terms
  • Contact

© 2026 HeyPsych. All rights reserved.

HeyPsych provides decision-support information. Not a substitute for professional medical advice.

Tools/Compare

SilverCloud by Amwell vs Akili Interactive (EndeavorRx, EndeavorOTC)

Show:
Detail:
Attribute
measurement-outcomes-dtx

SilverCloud by Amwell

Amwell (acquired SilverCloud Health)

measurement-outcomes-dtx

Akili Interactive (EndeavorRx, EndeavorOTC)

Akili Interactive (Subsidiary of Virtual Therapeutics)

SilverCloud by Amwell
Akili Interactive (EndeavorRx, EndeavorOTC)
Key Differencesat a glance
SilverCloud by Amwell:Purpose-built for mental health
SilverCloud by Amwell:More integrations (2)
Akili Interactive (EndeavorRx, EndeavorOTC):Purpose-built for mental health

Overview

Tool Name
SilverCloud by Amwell
Akili Interactive (EndeavorRx, EndeavorOTC)
Tool Name
SilverCloud by Amwell
SilverCloud by Amwell
Akili Interactive (EndeavorRx, EndeavorOTC)
Akili Interactive (EndeavorRx, EndeavorOTC)
What It Is
Digital CBT platform for depression, anxiety, and insomnia with 30+ clinical studies.
First FDA-cleared video game digital therapeutic for ADHD in children and adults.
What It Is
SilverCloud by Amwell
Digital CBT platform for depression, anxiety, and insomnia with 30+ clinical studies.
Akili Interactive (EndeavorRx, EndeavorOTC)
First FDA-cleared video game digital therapeutic for ADHD in children and adults.
Primary Category
measurement-outcomes-dtx
measurement-outcomes-dtx
Primary Category
SilverCloud by Amwell
measurement-outcomes-dtx
Akili Interactive (EndeavorRx, EndeavorOTC)
measurement-outcomes-dtx
Founded
Unknown
Unknown
Founded
SilverCloud by Amwell
Unknown
Akili Interactive (EndeavorRx, EndeavorOTC)
Unknown
Best For
Employers seeking evidence-based digital mental health for employees; Health plans implementing scalable behavioral health solutions; Health systems integrating digital therapeutics with telehealth
Pediatricians and child psychiatrists treating ADHD in children ages 8-17; Adult psychiatrists seeking non-pharmacological ADHD adjunct treatments; Parents looking for FDA-cleared, engaging ADHD interventions
Best For
SilverCloud by Amwell
Employers seeking evidence-based digital mental health for employees; Health plans implementing scalable behavioral health solutions; Health systems integrating digital therapeutics with telehealth
Akili Interactive (EndeavorRx, EndeavorOTC)
Pediatricians and child psychiatrists treating ADHD in children ages 8-17; Adult psychiatrists seeking non-pharmacological ADHD adjunct treatments; Parents looking for FDA-cleared, engaging ADHD interventions

Pricing

Starting Price
Custom quote required
$99/30 days (EndeavorRx) or $69.99/3 months (EndeavorOTC)
Starting Price
SilverCloud by Amwell
Custom quote required
Akili Interactive (EndeavorRx, EndeavorOTC)
$99/30 days (EndeavorRx) or $69.99/3 months (EndeavorOTC)
Pricing Model
enterprise-custom
Flat monthly
Pricing Model
SilverCloud by Amwell
enterprise-custom
Akili Interactive (EndeavorRx, EndeavorOTC)
Flat monthly
Free Trial
No free trial
No free trial
Free Trial
SilverCloud by Amwell
No free trial
Akili Interactive (EndeavorRx, EndeavorOTC)
No free trial
Pricing Details
Enterprise pricing through Amwell. Typically sold to employers, health plans, and health systems. Contact Amwell for custom quote.
EndeavorRx is prescription-only and FSA/HSA eligible. EndeavorOTC is available directly to consumers without prescription.
Pricing Details
SilverCloud by Amwell
Enterprise pricing through Amwell. Typically sold to employers, health plans, and health systems. Contact Amwell for custom quote.
Akili Interactive (EndeavorRx, EndeavorOTC)
EndeavorRx is prescription-only and FSA/HSA eligible. EndeavorOTC is available directly to consumers without prescription.

Compliance & Security

HIPAA Compliant
Yes
Yes
HIPAA Compliant
SilverCloud by Amwell
Yes
Akili Interactive (EndeavorRx, EndeavorOTC)
Yes
BAA Available
Yes
Unknown
BAA Available
SilverCloud by Amwell
Yes
Akili Interactive (EndeavorRx, EndeavorOTC)
Unknown
SOC 2 Certified
Yes
Unknown
SOC 2 Certified
SilverCloud by Amwell
Yes
Akili Interactive (EndeavorRx, EndeavorOTC)
Unknown
HITRUST Certified
Unknown
Unknown
HITRUST Certified
SilverCloud by Amwell
Unknown
Akili Interactive (EndeavorRx, EndeavorOTC)
Unknown

Features

Mobile App
Yes
No
Mobile App
SilverCloud by Amwell
Yes
Akili Interactive (EndeavorRx, EndeavorOTC)
No
Mental Health Specific
Yes
Yes
Mental Health Specific
SilverCloud by Amwell
Yes
Akili Interactive (EndeavorRx, EndeavorOTC)
Yes

Integrations

Total Integrations
2 integrations
None listed
Total Integrations
SilverCloud by Amwell
2 integrations
Akili Interactive (EndeavorRx, EndeavorOTC)
None listed

Support & Fit

Practice Sizes
Large (51-200), Enterprise (200+)
Solo, Small (2-10), Medium (11-50)
Practice Sizes
SilverCloud by Amwell
Large (51-200), Enterprise (200+)
Akili Interactive (EndeavorRx, EndeavorOTC)
Solo, Small (2-10), Medium (11-50)
Customer Base
Unknown
Unknown
Customer Base
SilverCloud by Amwell
Unknown
Akili Interactive (EndeavorRx, EndeavorOTC)
Unknown

Ready to Get Started?

Visit these tools to learn more or request a personalized demo.

Try SilverCloud by Amwell
Try Akili Interactive (EndeavorRx, EndeavorOTC)
Browse all tools
SilverCloud by Amwell
Akili Interactive (EndeavorRx, EndeavorOTC)